RTI-126 hydrochloride

High purity analytical reference standard

RTI-126 hydrochloride is a structurally defined compound from the group consisting of phenyltropanes or Tropan derivatives. The material is characterised for laboratory research, analytical chemistry and forensic applications. RTI-126 Also under the name RTI-4229-126 known.

The defined chemical structure and stereochemistry make RTI-126 particularly interesting for analytical investigations of tropane and phenyltropane derivatives.

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Product information

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Chemical description

RTI-126 belongs to the group of 3-Phenyltropane, a class of structurally related compounds studied in particular in medical chemistry and neuropharmacology.

The hydrochloride form is described as:

(1R,2S,3S,5S)-8-methyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)-3-phenyl-8-azabicyclo[3.2.1]octane monohydrochloride

designated.

The defined stereochemistry is particularly relevant in analytical studies, since structurally similar tropane derivatives can be distinguished by their stereochemical properties.

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Research and analytical applications

RTI-126 has been studied in scientific research. Phenyltropane derivatives and their interactions with monoamine transporter systems examined.

For professional laboratories, the material may be relevant in particular as a reference substance for the following activities:

• Development of analytical methods
• Chromatographic studies
• LC-MS and LC-MS/MS analysis
• GC-MS analysis
• Forensic toxicological research
• Structural identification
• Comparative studies with reference materials
• Chemical characterisation
• Quality control tests
• Basic pharmacological research

The specific suitability for an analytical method should be assessed against the relevant laboratory requirements and the available batch documentation.

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Analytical reference standard

RTI-126 hydrochloride is suitable for use in scientific and analytical laboratory environment provided.

For professional applications, the documents belonging to the respective lot should be checked. These include in particular:

Certificate of Analysis (CoA)
Batch-specific identity and purity information.

Safety Data Sheet (SDS)
information on hazards, handling, storage and disposal.

Analytical data
Where available, additional chromatographic or spectrometric characterisation.

Batch/lot number
To fully trace the material.

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Analytical Characterization

For the investigation and identification of RTI-126, different analytical methods can be used depending on the question, for example:

LC-MS · LC-MS/MS · GC-MS · HPLC · NMR

The actually available analysis results and specifications are always Batch specific documentation to be found.

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Physical & Chemical Properties

RTI-126 hydrochloride is provided as a solid. For the hydrochloride form, a molecular weight of 319,8 g/mol a reference purity of ≥98 % specified.

Other calculated chemical properties include:

• Exact mass: 319,1451 Da
• Number of hydrogen bridge donors: 1
• Number of hydrogen bridge acceptors: 4
• Number of rotatable bindings: 2
• Topological polar surface: 42,2 Å2

These parameters can be used to support the chemical identification and development of analytical methods.

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Storage and handling

For long-term storage, for RTI-126 hydrochloride, storage at -20 °C specified.

When handling, laboratories should in particular:

• keep the material in the appropriately labelled original container;
• comply with the storage conditions specified on the respective batch documentation,
• check the current SDS before use,
• use appropriate personal protective equipment;
• use appropriate technical protection measures;
• as well as the applicable requirements for documentation and inventory management.

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Quality documentation

Product documentation should be provided batch-by-batch for professional laboratory users.

Available documents may include:

• Certificate of Analysis (CoA)
• Safety Data Sheet (SDS)
• Batch/lot information
• Proof of identity
• Purity data
• analytical characterisation data, where available

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Important note

For research and analysis purposes only. Not intended for human or veterinary use.

RTI-126 is a pharmacologically active research chemical and may only be handled by suitably qualified personnel and under appropriate laboratory conditions.

Customers are responsible for the acquisition, possession, import, storage or use of the Legal and regulatory provisions applicable in the respective country to be checked. The legal classification can vary significantly between European countries.

RChemMart does not represent this product as a medicine, food supplement, food or therapeutic product.