RTI-126 hydrochloride

High purity analytical reference standard

RTI-126 hydrochloride is a structurally defined compound from the group consisting of phenyltropanes or Tropan derivatives. The material is characterised for laboratory research, analytical chemistry and forensic applications. RTI-126 Also under the name RTI-4229-126 known.

The defined chemical structure and stereochemistry make RTI-126 particularly interesting for analytical investigations of tropane and phenyltropane derivatives.

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Product information

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Chemical description

RTI-126 belongs to the group of 3-Phenyltropane, a class of structurally related compounds studied in particular in medical chemistry and neuropharmacology.

The hydrochloride form is described as:

(1R,2S,3S,5S)-8-methyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)-3-phenyl-8-azabicyclo[3.2.1]octane monohydrochloride

designated.

The defined stereochemistry is particularly relevant in analytical studies, since structurally similar tropane derivatives can be distinguished by their stereochemical properties.

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Research and analytical applications

RTI-126 has been studied in scientific research. Phenyltropane derivatives and their interactions with monoamine transporter systems examined.

For professional laboratories, the material may be relevant in particular as a reference substance for the following activities:

• Development of analytical methods
• Chromatographic studies
• LC-MS and LC-MS/MS analysis
• GC-MS analysis
• Forensic toxicological research
• Structural identification
• Comparative studies with reference materials
• Chemical characterisation
• Quality control tests
• Basic pharmacological research

The specific suitability for an analytical method should be assessed against the relevant laboratory requirements and the available batch documentation.

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Analytical reference standard

RTI-126 hydrochloride is suitable for use in scientific and analytical laboratory environment provided.

For professional applications, the documents belonging to the respective lot should be checked. These include in particular:

Certificate of Analysis (CoA)
Batch-specific identity and purity information.

Safety Data Sheet (SDS)
information on hazards, handling, storage and disposal.

Analytical data
Where available, additional chromatographic or spectrometric characterisation.

Batch/lot number
To fully trace the material.

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Analytical Characterization

For the investigation and identification of RTI-126, different analytical methods can be used depending on the question, for example:

LC-MS · LC-MS/MS · GC-MS · HPLC · NMR

The actually available analysis results and specifications are always Batch specific documentation to be found.

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Physical & Chemical Properties

RTI-126 hydrochloride is provided as a solid. For the hydrochloride form, a molecular weight of 319,8 g/mol a reference purity of ≥98 % specified.

Other calculated chemical properties include:

• Exact mass: 319,1451 Da
• Number of hydrogen bridge donors: 1
• Number of hydrogen bridge acceptors: 4
• Number of rotatable bindings: 2
• Topological polar surface: 42,2 Å2

These parameters can be used to support the chemical identification and development of analytical methods.

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Storage and handling

For long-term storage, for RTI-126 hydrochloride, storage at -20 °C specified.

When handling, laboratories should in particular:

• keep the material in the appropriately labelled original container;
• die auf der jeweiligen Chargendokumentation angegebenen Lagerbedingungen einhalten,
• das aktuelle SDS vor der Verwendung prüfen,
• geeignete persönliche Schutzausrüstung verwenden,
• geeignete technische Schutzmaßnahmen einsetzen,
• sowie die jeweils geltenden Anforderungen an Dokumentation und Bestandsführung beachten.

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Qualitätsdokumentation

Für professionelle Laboranwender sollte die Produktdokumentation chargenbezogen bereitgestellt werden.

Verfügbare Dokumente können umfassen:

• Certificate of Analysis (CoA)
• Safety Data Sheet (SDS)
• Chargen-/Lot-Informationen
• Identitätsnachweis
• Purity data
• analytische Charakterisierungsdaten, sofern verfügbar

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Important note

Ausschließlich für Forschungs- und Analysezwecke. Nicht für den menschlichen oder tiermedizinischen Gebrauch bestimmt.

RTI-126 ist eine pharmakologisch aktive Forschungschemikalie und darf ausschließlich durch entsprechend qualifiziertes Personal und unter geeigneten Laborbedingungen gehandhabt werden.

Kunden sind selbst dafür verantwortlich, vor Erwerb, Besitz, Einfuhr, Lagerung oder Verwendung die im jeweiligen Land geltenden gesetzlichen und regulatorischen Bestimmungen zu prüfen. Die rechtliche Einstufung kann zwischen europäischen Ländern erheblich variieren.

RChemMart stellt dieses Produkt nicht als Arzneimittel, Nahrungsergänzungsmittel, Lebensmittel oder therapeutisches Produkt dar.